Comfortology by BetterRX

Patient Resource Guide: Managing Constipation

Written by Rebecca Christensen, PharmD | Aug 6, 2025 5:30:00 PM

 While uncomfortable, constipation can be managed using one or more of several strategies designed to prevent and alleviate symptoms.

OVERVIEW OF CONSTIPATION

Constipation is a common issue for patients in hospice care, characterized by infrequent bowel movements and/or difficulty passing stool. It can be caused by various factors including medications, reduced mobility, dehydration, and dietary changes.

 

COMMON CAUSES OF CONSTIPATION IN THE HOSPICE SETTING

In hospice care, constipation often arises due to multiple factors such as:

 

COMMON CAUSES OF CONSTIPATION IN THE HOSPICE SETTING

Decreased physical activity

Decreased fluid intake

Decreased nutrition

Dietary changes

Pain medication side effect

Narrow bowel

 

COMMON SYMPTOMS OF CONSTIPATION

Constipation presents in a number of different ways, but not all symptoms experienced may be so obvious. While straining when having a bowel movement may be a clear indication, other symptoms like nausea or abdominal pain may be more difficult to connect to constipation, as other diseases may be associated with similar symptoms.

COMMON SYMPTOMS OF CONSTIPATION IN THE HOSPICE SETTING

Abdominal discomfort/pain

Infrequent bowel movements

Difficulty passing stool

Straining during bowel movements

Incomplete clearing of stool during bowel movements

Loss of appetite or decreased food intake

Abdominal bloating

Nausea or vomiting

Rectal bleeding

Hard or lumpy stool

Restlessness

Irritability

 

NON-MEDICATION MANAGEMENT FOR CONSTIPATION

TREATMENT

PROPOSED EXPLANATION FOR BENEFIT

Adequate Hydration

Ensuring sufficient fluid intake helps soften stool, making it easier to pass. If possible, aim for at least 8 cups per day

High-Fiber Diet

Foods rich in fiber, like fruits, vegetables and whole grains promote regular bowel movements

Activity

Gentle physical activity, if possible, aids in stimulating bowel function and reducing constipation

Consistent Bowel Routine

Establishing a regular time for bowel movements encourages consistency in the body’s natural rhythm

 

MEDICATION TREATMENT OPTIONS FOR MANAGING CONSTIPATION 

STIMULATING LAXATIVES

Medication 

Usual Adult Dose

Time to Action

Side Effects

Bisacodyl

10mg po daily

10mg rectally daily

6-10 hours

15-60 minutes

gastric irritation

rectal irritation

Senna

1-2 tablets (8.6mg/tab) po daily to BID

6-12 hours

gastric irritation, bloat

OSMOTIC LAXATIVES

Medication

Usual Adult Dose

Time to Action

Side Effects

Polyethylene Glycol (Miralax®)

8.5 (1/2 capful)-34g (2 capfuls) in 8oz

6-10 hours

15-60 minutes

nausea, bloating, cramping

Lactulose

10g/15mg to 20g/30ml up to BID

8-24 hours

abdominal bloating, flatulence

Sorbitol

30g (120mg of 25% solution) daily

24-48 hours

abdominal bloating, flatulence

Glycerin

1 suppository rectally daily

15-60 minutes

rectal irritation

Magnesium citrate

200ml (11.6g) po daily

30 minutes to 3 hours

watery stools, urgency, electrolyte abnormality

Magnesium hydroxide

5-15ml as needed up to 4 times daily

30 minutes to 6 hours

Magnesium sulfate

1-2 tsp (5-10g) in 240ml of water daily

30 minutes to 3 hours

STOOL SOFTENER

Medication

Usual Adult Dose

Time to Action

Side Effects

Docusate

100mg 1-2 times/day

24-72 hours

well tolerated

These medications work in different ways to prevent and/or treat constipation. Even if you or your loved one is not eating as much as they normally do, or than they did before getting sick, it is important they still have a bowel movement at least every 2-3 days.

Patients on opioid therapy (morphine, hydrocodone, oxycodone, hydromorphone, fentanyl or methadone) usually require regular use of a stimulating laxative (senna, sennosides or bisacodyl) in order to counteract the effect of the pain medication slowing bowel activity. Docusate (Colace) or polyethylene glycol (Miralax) alone are often not enough to prevent constipation when the patient is taking these pain medications.

If you have not had a bowel movement in three days or are feeling any of the constipation symptoms noted in the table above, please contact your hospice team so changes can be made to your medications to resolve the issue.

SUMMARY

To successfully manage constipation in the hospice care setting, a mixed approach to therapy is often required, using both non-medication approaches and medication. Understanding factors that contribute to constipation and using the appropriate medications can significantly reduce the risk of experiencing this uncomfortable (even dangerous) symptom.

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