Gastrointestinal symptoms are one of the most common problems that healthcare providers address when providing end-of-life care. Proton pump inhibitors (PPIs) are commonly used to treat gastroesophageal reflux disease (GERD) symptoms including heartburn, regurgitation, and epigastric pain. Many patients are admitted to hospice services already using acid reflux medications. While potentially useful in palliative care settings where further investigation of underlying disease may not be appropriate, these agents have significant side effects and carry an increased risk of complications that should be considered when reevaluating medication regimens, medication appropriateness, and deprescribing. Read More...