Consistent medication ordering decisions. Predictable costs.
BetterRX Guardrails help standardize medication decisions and improve pharmacy spend visibility across teams and locations.
BetterRX Guardrails Are Easy to Configure
Guardrail Manager™ for Clinical Leaders
The Guardrail Manager provides clinical leaders with centralized management over their BetterRX Guardrails across their organization. Medication choices reflect best practices and align with your philosophy of care.
- Confidence in team decisions
- Account- and facility-level flexibility
- Spend less time training your nurses

More Time for Patient Care
Simplify Frontline Decisions for Nurses.
BetterRX Guardrails reduce cognitive load for nurses with clearer guidance up front, helping improve medication workflow management and hospice care coordination.
Your nurses did not join hospice to babysit pharmacy spend.
Give nurses clear guidance
Improve nurse workflow efficiency
Proactive Cost Control
Achieve Confidence in Your PPD
-8% Deliveries/Patient Median*
*Among hospices with low override rates (<40%)
Built for your goals, not PBM drug margins
BetterRX Guardrails align medication guidance with hospice-defined best practices — not PBM margins or pharmacy markups.
Your rules, your goals, your BetterRX Guardrails.
Focus on care quality and cost goals
You configure your BetterRX Guardrails
Real-time visibility into spend
Frequently Asked Questions
Others frequently ask…-
BetterRX Guardrails are a configurable clinical standard embedded directly into a hospice's medication ordering workflow. Rather than relying on training materials or policy manuals that clinicians must recall from memory during a patient encounter, BetterRX Guardrails TM present best- practice defaults at the moment a prescription is being placed. For example, with one medication ordering guardrail called Interchange Manager, clinical leaders can set and adjust pre-approved therapeutic alternatives in one place. Then, when a clinician selects a high-cost medication where a pre-approved lower-cost clinical equivalent (or interchange) is available, the system automatically presents the hospice's designated alternative before submission. Clinicians retain full autonomy to choose differently, but they do so with complete visibility into cost and formulary implications, and any exception is briefly documented, creating a data trail for clinical leadership. -
Pharmacy medication cost per patient per day (PPD) varies considerably across hospice organizations based on census size, patient acuity, geography, and the rigor of formulary management. Published industry data and academic research suggest that pharmacy-specific medication costs generally run in the range of $10 to $15 per patient per day under well- managed formulary conditions, though organizations without active formulary oversight can run meaningfully higher. The most actionable benchmark for any individual hospice is its own trend line: high-performing organizations prioritize minimizing day-to-day PPD volatility so that no single ordering decision creates a monthly cost spike. BetterRX client data shows organizations commonly achieving generic utilization rates above 95%. -
Traditional pharmacy benefit managers (PBM) typically operate on a spread pricing model, in which the PBM bills the hospice a higher amount than it pays the dispensing pharmacy and retains the difference as revenue. This spread is generally
invisible to the hospice: without claim-level transparency, an organization has no way to know how much of its pharmacy
spend is going to the PBM rather than the pharmacy. In a pass-through
model, the hospice pays the actual pharmacy acquisition and dispensing costs directly, plus a clearly disclosed administrative fee per claim, with no hidden spread. Pass-through pricing gives hospice financial and clinical leaders
full visibility into true drug costs, enabling accurate formulary analysis, PPD forecasting, and identification of substitution opportunities that spread-pricing models structurally obscure. -
Savings from improved formulary compliance depend on an organization's medication utilization, census size, and current prescribing patterns. Every dollar of pharmacy cost saved under Medicare's fixed per-diem model flows directly to organizational margin, because reimbursement is identical regardless of drugnspend. In a documented BetterRX case study, Compassion Hospice
reduced pharmacy spend by $1.80 per patient per day after implementing Interchange Manager, with their team reporting no negative impact on patient care.⁸ For reference, that reduction
across a 100-patient census would represent approximately $65,700 in annualized pharmacy savings. These figures are selfreported
and outcomes will vary by organization; they are best understood as illustrative of what disciplined formulary
management can achieve rather than as guaranteed results. -
Hospice pharmacy costs spike for predictable structural reasons. After-hours and weekend ordering creates the highest risk, as coverage clinicians default to familiar choices rather than organization-specific formulary standards when no realtime guidance is available. Clinicians ordering under acute cognitive load, managing multiple patient crises simultaneously, tend to select higher-cost branded or intravenous formulations
when equally effective oral generics exist. Staff turnover creates recurring knowledge gaps, as new hires lack the formulary
fluency of experienced colleagues. The most effective prevention is structural rather than educational. Embedding
approved defaults and real-time alternative alerts directly into the ordering workflow ensures formulary-aligned decisions occur consistently regardless of shift, experience level, or cognitive load. Monthly retrospective reports and periodic
reminders to "be cost-conscious" have limited impact because they operate outside the decision moment rather than within it. -
Workflow-embedded clinical decision support means that best-practice guidance appears automatically within the tools clinicians already use to place orders, rather than in separate reference materials, policy manuals, or training courses they
must separately consult. In the hospice medication workflow, this means a nurse sees real‑time cost information, hospice‑preferred medication selections, and formulary status for every order
without leaving the screen or calling the pharmacy. BetterRX Guardrails also manage ancillary fee exposure by
automatically consolidating orders and limiting STAT or After‑Hours use to medications that truly require it, reducing
unnecessary fees while keeping care moving smoothly. The support is non-blocking: it informs without interrupting, and the clinician retains full decision authority. Any deviation from the
suggested default is briefly documented, which creates a data trail that clinical directors can use for targeted, specific coaching conversations. This approach is structurally different from training-based methods, which place the entire cognitive burden of recall on the individual clinician at the moment of highest stress.




